Last update
5/16/2026
Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%
📅 Last updated:

Top Medical Research Studies

We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.

Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.

However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.
Read More
7
Vitamin A promotes vascular repair via JWA protein activation
Researchers investigated whether a form of vitamin A called atRA could help treat obstructive sleep apnea by studying rat models and cell cultures exposed to interrupted oxygen. They found that atRA boosts production of a protein called JWA, which reduces harmful oxidative stress damaging blood vessel linings in the lungs.

This oxidative stress reduction appears to restore normal function and growth of damaged blood vessels—a key problem in sleep apnea patients who often develop dangerous high blood pressure in their lungs. While these promising lab results suggest atRA could become a new treatment option for sleep apnea, further research in human patients would be needed to confirm these findings and establish safe, effective doses.
Read More

Most Useful Reviews

7.5
Uncertain effects
I'm not sure yet, but I've been struggling to sleep well. I purchased it after reading reviews claiming it could help improve sleep quality.
Read More
7.5
Reduced dryness
Helpful! It assists me in alleviating dry mouth during sleep while on a ketogenic diet.
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.

Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.

However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.
Read More
7
Vitamin A promotes vascular repair via JWA protein activation
Researchers investigated whether a form of vitamin A called atRA could help treat obstructive sleep apnea by studying rat models and cell cultures exposed to interrupted oxygen. They found that atRA boosts production of a protein called JWA, which reduces harmful oxidative stress damaging blood vessel linings in the lungs.

This oxidative stress reduction appears to restore normal function and growth of damaged blood vessels—a key problem in sleep apnea patients who often develop dangerous high blood pressure in their lungs. While these promising lab results suggest atRA could become a new treatment option for sleep apnea, further research in human patients would be needed to confirm these findings and establish safe, effective doses.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Uncertain effects
I'm not sure yet, but I've been struggling to sleep well. I purchased it after reading reviews claiming it could help improve sleep quality.
Read More
7.5
Reduced dryness
Helpful! It assists me in alleviating dry mouth during sleep while on a ketogenic diet.
Read More

Frequently Asked Questions

7.5
Uncertain effects
I'm not sure yet, but I've been struggling to sleep well. I purchased it after reading reviews claiming it could help improve sleep quality.
7.5
Reduced dryness
Helpful! It assists me in alleviating dry mouth during sleep while on a ketogenic diet.
We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.

Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.

However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.

References

  1. Saruhan E, Sertoglu E, Unal Y, Bek S, Kutlu G. The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea. Sleep Breath. 2021;25:923. 10.1007/s11325-020-02207-w
  2. Yan Y, Lan J, Zhang H, Ren Y, Cheng X, et al. JWA mediates oxidative stress to promote vascular endothelial repair in obstructive sleep apnea-hypopnea syndrome. Sleep Med. 2025;134:106686. 10.1016/j.sleep.2025.106686
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